BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R01 Clinical Trial Not Allowed)

This grant supports transformative, mechanistic research to understand how dynamic activity of individual neurons and neuronal ensembles in spatially organized brain networks produces internal experiences and observable behaviors. It funds studies that use invasive human surgical procedures such as intracranial recording or stimulation, optionally combined with complementary experimental models to deepen mechanistic insight.