Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)

This grant supports collaborative basic, translational, and clinical research to identify mechanisms of cancer therapy-induced adverse sequelae, clinically characterize them, and develop therapeutic approaches to prevent or reduce long-term effects. Projects should include mechanistic studies with translational endpoints and longitudinal clinical phenotyping to validate biomarkers, imaging, or patient-reported outcomes for future trials.