Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)

This grant supports developing and operating a Clinical Coordinating Center for investigator-initiated multi-site clinical trials, including efficacy, comparative effectiveness, pragmatic, and dissemination/implementation science studies. It funds the scientific rationale, operational planning, project management, recruitment, milestones, trial conduct, and result dissemination, especially for trials using innovative designs such as platform, adaptive, or Bayesian approaches.