Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)

This grant supports highly innovative mechanistic research to accelerate precision probiotic interventions by identifying host biological patterns that influence probiotic responses. It funds an initial phase to characterize these patterns using observational or secondary data, followed by a second phase to test their ability to improve probiotic responsiveness in mechanistic studies with animal models or humans.