NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)
This grant supports investigator-initiated early-phase clinical trials of natural products such as botanicals, probiotics, and dietary-supplement-type compounds that have strong scientific rationale and preliminary evidence. It funds milestone-driven testing of pharmacokinetics, bioavailability, mechanism of action, and target engagement, with up to three years for each phase.
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