Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)

This grant supports the adaptation and clinical validation of molecular, cellular, or imaging biomarkers for cancer detection, diagnosis, prognosis, monitoring, treatment response prediction, and cancer control or prevention. It funds research that acquires well-annotated specimens from clinical trials or observational cohorts to validate assays, encouraging multidisciplinary teams including assay developers, clinicians, statisticians, and clinical laboratory scientists.